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The Epothilones: An Outstanding Family of Anti-Tumor Agents: From Soil to the Clinic (Fortschritte der Chemie organischer Naturstoffe Progress in the Chemistry of Organic Natural Products)

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 |  2010-12-13 | Original language:English | PDF # 1 |  9.25 x.64 x6.10l,.85 | File type: PDF | 260 pages

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Epothilones have received unusual attention over the past ten years. They are novel antitumor drugs which very much like their predecessor paclitaxel (Taxol) act via microtubule stabilization. In comparison to paclitaxel and a number of alternative drugs with a similar mode of bioaction (e.g. laulimalide, eleutherobin, peluroside, discodermolide) the epothilones have significant advantages, above all very high activity in the nanomolar range and low susceptibility toward...

You can specify the type of files you want, for your gadget.The Epothilones: An Outstanding Family of Anti-Tumor Agents: From Soil to the Clinic (Fortschritte der Chemie organischer Naturstoffe Progress in the Chemistry of Organic Natural Products)   |  From Springer. A good, fresh read, highly recommended.

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