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Synthesis and Reactivity of Donor-Acceptor Substituted Aminocyclopropanes and Aminocyclobutanes (Springer Theses)

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 |  Florian de Nanteuil |  2015-09-27 | Original language:English | PDF # 1 |  9.21 x.75 x6.14l,.0 | File type: PDF | 315 pages

 | Synthesis and Reactivity of Donor Acceptor Substituted Aminocyclopropanes and Aminocyclobutanes Springer Theses

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This thesis presents a general approach to accessing nitrogen-substituted hetero- and carbocycles. In short, the annulation reactions developed in the thesis make it possible to access nitrogen-substituted four-, five- and six-membered rings, all essential building blocks for the synthesis of bioactive molecules. Many natural products display a saturated polycyclic core allowing a well-defined arrangement of functional groups in space. As such, they can interact with bio...

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