[PDF.79zd] Steric Fit in Quantitative Structure-Activity Relations (Lecture Notes in Chemistry)

Steric Fit in Quantitative Structure-Activity Relations (Lecture Notes in Chemistry)

[PDF.jh14] Steric Fit in Quantitative Structure-Activity Relations (Lecture Notes in Chemistry)

Steric Fit in Quantitative  A.T. Balaban, A. Chiriac, I. Motoc, Z. Simon epub
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 |  Springer |  1980-05-06 | Original language:English | PDF # 1 |  9.61 x.45 x6.69l,.71 | File type: PDF | 178 pages

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Although the importance of steric fit for receptor-effector 1 interactions was recognized since Emil Fischer proposed his "lock and key" theory, the whole area of steric properties is still in a very 2-4 early stage of development. We have a fairly good idea about el- tronic and hydrophobic parameters, but it is not easy to describe ste ric shapes of molecules without a large number of data. There are se veral cases of good QSAR's developed for rather large series of mol...

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