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Pharmacokinetic Profiling in Drug Research

Bernard Testa, Stefanie D. Krämer, Heidi Wunderli-Allenspach, Gerd Folkers




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 | #5191611 in Books |  Wiley-VCH |  2006-03-10 | Original language:English | PDF # 1 |  10.12 x1.17 x6.63l,3.03 | File type: PDF | 500 pages

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Informatics and robotics are the workhorses of a technological revolution in drug research. On them are based combinatorial chemistry, which yields compounds by the many thousands, and high-throughput bioassays, which screen them for activity. The results are avalanches of 'hits', which invade the databases like swarms of locusts. But far from being a plague, these innumerable compounds become a blessing if properly screened for 'drugability', i.e., for 'drug-like' prope...

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