[PDF.59rt] Peptidomimetics Protocols (Methods in Molecular Medicine)

Peptidomimetics Protocols (Methods in Molecular Medicine)

[PDF.hm19] Peptidomimetics Protocols (Methods in Molecular Medicine)

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 | #13753397 in Books |  2010-11-09 | Original language:English | PDF # 1 |  9.02 x1.31 x6.10l,1.85 | File type: PDF | 549 pages

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Many physiologically important receptors and enzymes are regulated by their endogenous ligands and inhibitors. Nature chose to utilize these p- tides as chemical switches since they can be efficiently synthesized and - graded in cells, thus providing an immediate response to a fast changing environment. Such properties, so critical in cell survival, make peptides less than ideal drug candidates. Other frequently desired properties in drug m- ecules include oral bioavaila...

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