[PDF.67zn] PEGylated Protein Drugs: Basic Science and Clinical Applications (Milestones in Drug Therapy)

PEGylated Protein Drugs: Basic Science and Clinical Applications (Milestones in Drug Therapy)

[PDF.sb71] PEGylated Protein Drugs: Basic Science and Clinical Applications (Milestones in Drug Therapy)

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 | #4371970 in Books |  2009-10-23 | Original language:English | PDF # 1 |  9.30 x.90 x6.30l,1.85 | File type: PDF | 290 pages

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PEGylation technology and key applications are introduced by this topical volume. Basic physical and chemical properties of PEG as basis for altering/improving in vivo behaviour of PEG-conjugates such as increased stability, improved PK/PD, and decreased immunogenicity, are discussed. Furthermore, chemical and enzymatic strategies for the coupling and the conjugate characterization are reported. Following chapters describe approved and marketed PEG-proteins and PEG-ol...

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