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Lead-Seeking Approaches (Topics in Medicinal Chemistry)

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 | #15570174 in Books |  Springer |  2012-02-25 |  2012-03-14 | Original language:English | PDF # 1 |  9.26 x.55 x6.11l,.0 | File type: PDF | 217 pages

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High quality leads provide the foundation for the discovery of successful clinical development candidates, and therefore the identi?cation of leads is an essential part of drug discovery. The process for the identi?cation of leads generally starts with the screening of a compound collection, either an HTS of a relatively large compound collection (hundreds of thousands to one million plus compounds) or a more focused screen of a smaller set of compounds that have been pr...

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