[PDF.80nu] Development of New Radical Cascades and Multi-Component Reactions: Application to the Synthesis of Nitrogen-Containing Heterocycles (Springer Theses)

Development of New Radical Cascades and Multi-Component Reactions: Application to the Synthesis of Nitrogen-Containing Heterocycles (Springer Theses)

[PDF.vo91] Development of New Radical Cascades and Multi-Component Reactions: Application to the Synthesis of Nitrogen-Containing Heterocycles (Springer Theses)

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 |  2016-10-21 |  2016-09-03 | Original language:English | PDF # 1 |  9.25 x.82 x6.10l, | File type: PDF | 326 pages

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In this dissertation, Marie-Hélène Larraufie develops original radical and pallado-catalyzed methodologies to enable the synthesis of several classes of bioactive nitrogen-containing heterocycles. New radical cascades employing the N-acylcyanamide moiety offer straightforward routes to quinazolinones and guanidines, as well as new insights into the mechanism of homolytic aromatic substitutions. In parallel, Larraufie expands the scope of visible light photo...

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