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Development of New MDR-Tuberculosis Drugs (Pharmacology - Research, Safety Testing and Regulation)

Jarmila Vinsova, Martin Kratky




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 | #14883984 in Books |  2010-09-30 | Original language:English | PDF # 1 |  8.75 x5.75 x.25l,.0 | File type: PDF | 98 pages

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The emergence of resistance to anti-tuberculosis drugs, particularly of MDR-TB and newly XDR-TB, has become a major public health problem. The current treatment regiment has several disadvantages, i.e. long treatment period (DOTS takes minimum 6 months) during which tubercle bacilli mutant become resistant to one or more drugs; side effects of the used drugs; co-infection of HIV/AIDS. The emergence of MDR-TB has made many currently available anti-TB drugs ineffective. Sl...

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