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Copper-Catalyzed Multi-Component Reactions: Synthesis of Nitrogen-Containing Polycyclic Compounds (Springer Theses)

Yusuke Ohta




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 |  2013-02-24 |  2013-02-24 | Original language:English | PDF # 1 |  9.25 x.28 x6.10l,.39 | File type: PDF | 104 pages

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A copper-catalyzed direct synthesis of 2-(aminomethyl)indoles by catalytic domino reaction including multi-component coupling was developed, and is the first example of a three-component indole formation without producing salts as a byproduct. Based on this reaction, a copper-catalyzed synthesis of 3-(aminomethyl)isoquinoline was accomplished which represents an unprecedented isoquinoline synthesis through a four-component coupling reaction. Following these results, exte...

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