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Computational Toxicology: Chapter 7. Computational Translation of Nonmammalian Species Data to Mammalian Species to Meet REACH and Next Generation Risk Assessment Needs

Edward J. Perkins, Natàlia Garcia-Reyero




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 |  2013-06-04 |  2013-06-04 | File type: PDF

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New concepts in toxicology facilitate the use of nonmammalian vertebrate species (e.g., fish) and nonanimal models (nonvertebrates, early embryo vertebrates, or cell-based) as surrogates for mammals. We present a strategy to translate nonmammalian species data to estimate potential impact of chemicals on mammalian species based on highly conserved proteins and biological pathways linked to a defined adverse effect. Protein “targets” and pathway-level informat...

You easily download any file type for your gadget.Computational Toxicology: Chapter 7. Computational Translation of Nonmammalian Species Data to Mammalian Species to Meet REACH and Next Generation Risk Assessment Needs   |  Edward J. Perkins, Natàlia Garcia-Reyero. I was recommended this book by a dear friend of mine.

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