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Anti-Cancer N-Heterocyclic Carbene Complexes of Gold(III), Gold(I) and Platinum(II): Thiol “Switch-on” Fluorescent Probes, Thioredoxin Reductase ... Reticulum Targeting Agents (Springer Theses)

Taotao Zou




[PDF.zm93] Anti-Cancer N-Heterocyclic Carbene Complexes of Gold(III), Gold(I) and Platinum(II): Thiol “Switch-on” Fluorescent Probes, Thioredoxin Reductase ... Reticulum Targeting Agents (Springer Theses)

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 |  2016-02-19 | Original language:English | PDF # 1 |  9.21 x.44 x6.14l,.0 | File type: PDF | 164 pages

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This thesis focuses on the development of gold- and non-classical platinum-based anti-cancer agents that display distinctively different anti-cancer mechanisms compared to the commonly used cisplatin. These metal complexes contain N-heterocyclic carbene (NHC) ligands which are able to form strong M-C(NHC) bonds, conferring high stability and favorable lipophilicity, reactivity and binding specificity of metal complexes on biomolecules. The author demonstrates signific...

You easily download any file type for your gadget.Anti-Cancer N-Heterocyclic Carbene Complexes of Gold(III), Gold(I) and Platinum(II): Thiol “Switch-on” Fluorescent Probes, Thioredoxin Reductase ... Reticulum Targeting Agents (Springer Theses)   |  Taotao Zou.Not only was the story interesting, engaging and relatable, it also teaches lessons.

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